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Unique sterilising and depyrogenation tunnels

A Biopharma Process Systems product story
Edited by the Processingtalk editorial team Dec 24, 2004

PennTech tunnels are designed to continuously sterilise and depyrogenate pharmaceutical glass containers in a class 100 environment, with increased energy efficiency

The NEW PennTech sterilising and depyrogenation tunnels are now available in the UK and Ireland.

PennTech's laminar airflow tunnels have been designed to continuously sterilise and depyrogenate pharmaceutical glass containers in a class 100 environment with increased energy efficiency.

The Tunnels comprise of three chambers: the Infeed Chamber, the Sterilising Chamber and the Cooling Chamber.

The Infeed Chamber creates a thermal barrier between the vial washing room and the Sterilising Chamber, to protect the vials from contamination and to pre-heat the vials.

Vertical unidirectional HEPA-filtered air blows over the vials.

The Infeed Chamber is pressurised compared to the room but less than the Sterilising Chamber.

This small pressure drop allows for some hot air to flow from the Sterilising Chamber to the Infeed Chamber for drying and pre-heating of the vials.

The Sterilising Chamber is fully insulated and can be heated up to temperatures of 350C (660F).

The small pressure drop between the sterilising chamber and the cooling chamber causes a counterflow between these sections In the Cooling Chamber, one or two cooling coils assist in the cooling of the vials to ambient temperature.

Regular tap water or chilled water may be used.

The dwell time in the cooling chamber is vial dependent.

PennTech sterilising tunnels are PLC controlled with a simple-to-use menu-driven operator-machine interface.

Additional software can be used for system validation according to 21 CFR part 11.

All PennTech sterilising tunnels are fully compatible with PennTech vial washers and trayloaders and may be integrated into other existing or new installations.

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