Product category:
Process Control and Monitoring Systems
News Release from: Emerson Process Management | Subject: PlantWeb Architecture at Indena
Edited by the Processingtalk Editorial
Team on 30 April 2003
Anti-cancer drug manufactured using
PlantWeb
Italian company Indena looks to Emerson pharmaceutical expertise and technology to automate its manufacturing of anti-cancer compound, at plant in Settala, near Milan
Indena is the world's leading company dedicated to identifying, developing and producing active ingredients from plants for use in the pharmaceutical and health industries They are one of the main suppliers of a potential new anti-cancer compound that has been approved by the FDA for phase 1 clinical trials
This article was originally published on Processingtalk on 29 Aug 2008 at 8.00am (UK)
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Emerson is a leader in engineering and implementing pharmaceutical automation solutions including conformance to FDA code of practice, 21CFR Part 11.
Emerson have implemented the automation solution for Indena based on PlantWeb digital plant architecture including a DeltaV digital automation system, using Foundation fieldbus technology.
The Settala facility extracts the anti-cancer compound from the leaves of a plant, then supplies the extracted product to a major pharmaceutical company for processing into the finished drug.
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Indena chose Emerson as a partner for several reasons.
Indena wished to work with a large company that was able to guarantee continuous support as well as a company that was offering a technically advanced solution based on open protocols.
Emerson was asked to supply a flexible, open system based on fieldbus technology that could be used to control the process as well as managing the instrumentation assets.
Ing Piotti of Indena believes that it is essential for modern systems to do both.
"It is clear that for companies to be competitive in the future they will have to adopt a total plant vision and architecture that supports both the process control aspect and instrumentation maintenance".
Further requirements imposed by Indena were that the supplied automation system should have an easy and effective programming interface as well as having software tools that are easy to learn.
It was specified that the digital information from the field instruments should be able to be used to optimise the process as well as for predictive maintenance.
"At the moment, the PlantWeb architecture from Emerson is the best solution for complete automation," Piotti said.
"Moreover, Emerson is able to give not only high quality automation solutions, but also loyalty - a new trust relationship between client and supplier".
Manufacturing at the Settala facility is based on a high precision batch operation.
In order to control and manage this process, Emerson worked with Indena staff to install and configure the DeltaV digital automation system.
The DeltaV system and DeltaV Batch software are built for batch control solutions.
They provide powerful functionality, and easy, cost-effective engineering and operations interface.
AMS predictive maintenance software within DeltaV provides functionality that enables easy reproduction of device calibration certificates for past calibrations, documentation of test scheme changes, and AMS system administrator events.
Indena have calculated that during the installation phase of the project alone they saved 50% of the cost when compared to a more traditional approach to plant architecture.
These savings were as a result of reduced wiring and installation costs as well as a reduction in time spent commissioning by utilising the digital communication capabilities of the field instruments.
In addition to initial savings, Indena expect to see savings across the whole lifecycle of their plant.
The PlantWeb architecture is modular and scalable and can be expanded at low cost should future requirements demand.
Savings can be made in engineering and programming time through the use of easy graphic tools, such as block program language (IEC 1131).
The PlantWeb architecture is based around open protocols so that should they wish to, Indena can use instrumentation from various suppliers.
The use of AMS software can help to reduce the need for programmed maintenance.
AMS monitors device status and alerts and can present the information on the DeltaV workstation, enabling a predictive approach to maintenance to be adopted.
AMS can also be used to configure the field instruments as well as managing their calibration; it stores historical data allowing graphical trends to be produced that help to identify potential problem devices.
The streamlined maintenance activities that are possible as a result of utilising the capabilities of AMS can help to reduce unnecessary costs as well as minimising unplanned failures.
The result is increased profitability and an improved plant lifecycle.
The equipment that has been installed consists of 4 DeltaV controllers, with redundancy, handling 1400 I/O.
They are supervised by one engineering workstation and four field operator stations.
Plant expansions or upgrades are simplified by the DeltaV plug and play approach that not only means reduced installation time for new plants, but also minimised shutdowns for upgrades.
Indena staff were provided with operation training in a very short time.
In the future, Emerson will provide technical support by remote connection should the extensive on-line help facility not provide the answer to any problem. Request a free brochure from Emerson Process Management ...
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