Product category:
Containment systems, Leak protection
News Release from: Hosokawa Micron | Subject: Wet chemistry isolators
Edited by the Processingtalk Editorial
Team on 21 February 2008
Wet chemistry isolators offer barrier
protection
Hosokawa Micron wet chemistry isolator technology helps companies involved in chemical synthesis, offering barrier protection systems to safeguard personnel from potentially hazardous substances
Typically for enclosure of small scale bulk active pharmaceutical manufacturing plants incorporating reaction vessels, crystallisation equipment and filtration vessels, the isolators give easy but contained operator access for product input, product removal, operational adjustment and maintenance In response to health and safety concerns for personnel working directly with the liquid forms of increasingly concentrated active, toxic ingredients used in pharmaceutical production, the isolators offer flexibility of operation, product integrity and personnel protection at the highest level
This article was originally published on Processingtalk on 13 Nov 2003 at 8.00am (UK)
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A recent development in conjunction with a leading custom synthesis company comprised a single chamber isolator offering two modes of operation.
The isolator mode provides OELs of 0,1mcg/m TWA and an airflow mode provides OELs of 0,200mcg/m TWA by the use of inflow air velocity through the doors.
As an additional safety feature because solvents were used in the process, the isolator was designed to ensure any solvent vapour concentration remains below the lower explosion limit.
Within the isolator are shelves and dishes to retain small process components, canisters, batch reagents or other products which precludes the need for open door access for most operator process intervention.
All process services are piped to the isolator and connected outside the isolator.
The isolator is fully equipped with spray balls and lance for complete CIP operation with the cleaning liquid fully discharged to drain.
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