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Product category: Liquid Analysis: Titration, HPLC, IC
News Release from: Metrohm UK | Subject: Ion Chromatography
Edited by the Processingtalk Editorial Team on 17 October 2003

Determination of halides, organic acids
and anions

Ion Chromatography application note for the determination of halides, organic acids and other anions after combustion for elemental analysis

Ion Chromatography application note for the determination of halides, organic acids and other anions after combustion for elemental analysis Elemental analysis using combustion for sample preparation is a popular analysis in the pharmaceutical industry for drug development and QC work

Halide analysis is commonly performed colorimetrically or by titration.

However this involves the addition of hazardous hydrazinium compounds to the samples and the methods used are often fraught with interferences if samples contain a lot of ionic compounds.

Ion Chromatography (IC) has rarely been used for the post-combustion analysis of halides and other anions due to the high cost of instrumentation compared to traditional methods.

The introduction of the Metrohm range of Compact Ion Chromatography systems, now allows IC analysis to be performed at the prices approaching that of titration and other classical wet chemistry techniques.

Metrohm Application Notes N-4, S1-19 and S-78 describe the analysis of halides and organic acids using both suppressed and unsuppressed IC methods. Request a free brochure from Metrohm UK ...

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