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Pharmaceutical Processing News
News Release from: Metrohm UK | Subject: Pharm PAC
Edited by the Processingtalk Editorial
Team on 20 August 2004
Analytical companion for pharmaceutical
processes
Pharm PAC is billed as the professional companion for the determination of pharmaceutical ingredients.
Pharm PAC is billed as the professional companion for the determination of pharmaceutical ingredients Pharm PAC stands for pharmaceutical potentiometric analysis collection
This article was originally published on Processingtalk on 2 Jul 2008 at 8.00am (UK)
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It contains the titration methods most used in the pharmaceutical industry in an attractive and practical form.
Know-how package for the determination of pharmaceutical ingredients The 35 methods delivered with this package can easily be loaded into a Metrohm Titrino or Titrando titrator.
Aqueous acid-base titrations cover: direct titrations; titrations with bases; titrations with acids; and indirect titrations (back titrations).
Nonaqueous acid-base titrations cover: alkaline titrants, in ethanol, with HCl addition, in dimethylformamide (DMF), in acetone, in pyridine, in ethanol or methanol, and in special solvents; and acidic titrants, in glacial acetic acid, with HClO4, in glacial acetic acid/acetic anhydride, with HClO4, in acetic anhydride, with HClO4, in glacial acetic acid plus Hg acetate, with HClO4, in glacial acetic acid/MEK, with HClO4, in formc acid/glacial acetic acid or acetic anhydride, with HClO4, and in other solvents or solvent mixtures.
Redox titrations encompass: iodine/thiosulfate (iodometry); iodine/arsenite (iodometry); diazotization with NaNO2; Cer(IV) (cerimetry); KBrO3 (bromatometry); KMnO4 (permanganometry); KIO3; and reducing sugars.
Precipitation titrations cover AgNO3 (argentometry) and surfactant titrations.
Photometric EDTA titrations (chelometry/complexometry) are covered.
Characteristic numbers of fats and oils include: acid value and free fatty acids (FFA); hydroxyl value; iodine value; peroxide value; and saponification value.
A further procedure covers qualification of the titrator forr validation of a titration method.
The methods included in the Metrohm Pharm PAC take into account the latest standards.
They apply the most appropriate methods and they use the Metrosensors especially developed for nonaqueous titrations.
By using these methods directly as SOPs (standard operating procedures) users can save both time and money.
Pharm PAC comprises a ring binder with detailed method descriptions, method memory card, CD ROM with Pharm PAC methods and Metrodata software CD. Request a free brochure from Metrohm UK ...
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