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News Release from: Microfluidics
Edited by the Processingtalk Editorial
Team on 13 March 2006
High shear fluid processors
Microfluidics will showcase two of its most popular laboratory high shear fluid processors, the M-110Y and M-110EH-30 Microfluidiser processors, at the ACHEMA 2006 show
Microfluidics will showcase two of its most popular laboratory high shear fluid processors, the M-110Y and M-110EH-30 Microfluidiser processors, at the ACHEMA 2006 Conference from May 15-19 in Frankfurt, Germany The M-110Y is a pneumatic bench top version, while the M-110EH-30 is a plug-in electric-hydraulic floor model on wheels, rounding out a comprehensive line of lab machines meeting CE requirements for cell disruption, formulation development and other fluid processing applications
This article was originally published on Processingtalk on 29 Aug 2005 at 8.00am (UK)
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The M-110Y is an easily portable lab machine that provides an order of magnitude higher shear rate than any available fluid processor on the market today.
The M-110Y processor maximises the energy-per-unit fluid volume insuring the generation of uniform, submicron particle and droplet sizes.
Process pressures are highly variable and reproducible, ranging from a low of 1,500 psi to a high of 23,000 psi.
Further reading
Scaling up from the lab to commercial production
Innovators in the pharmaceutical, biotechnology, chemical, personal care and food industries often face significant challenges in scaling up production to commercial quantities
Reduces particles and droplets to sub-micron sizes
The M-710 Microfluidiser processor model reduces particles and droplets to sub-micron sizes in a single pass, offering a cost-effective scale-up alternative
Options available for the M-110Y include a NIST traceable pressure transducer and thermocouple and accessories allowing pressurised sample feed.
Designed to operate reliably and efficiently at customer selected pressures of up to 30,000 psi process pressure, the M-110EH-30 is beneficial to the production of nano-suspensions and nano-emulsions as well as cell disruption with the least number of passes.
Additionally, more efficient processing of pharmaceutical formulations, fine chemicals, and biological material ranging from simple oil-in-water emulsions to highly immiscible solids-in-liquid suspensions will result.
Both the M-110EH-30 and the M-110Y Microfluidiser processors utilise the now well-established proprietary interaction chambers that are specifically designed with fixed-geometry, wear-resistant micro channels that accelerate the product stream to high velocities.
This process creates controlled and reproducible shear and impact forces that bring about the desired results.
Because the interaction chamber employs no moving parts, no disassembly is required for cleaning.
As a result of the Microfluidics' fixed geometry interaction chamber, both systems are capable of processing a wide variety of fluids ranging from simple oil-in-water emulsions to highly immiscible solids-in-liquid suspensions.
This broad range of capabilities provides an extensive number of options for formulating new lead drug candidates, thereby hastening the drug development process.
Additionally, each processor is easy to operate and designed for clean-in-place procedures.
These features facilitate the use of these systems for cell disruption, virtually eliminating sample cross-contamination.
Because each Microfluidics unit is process repeatable and scale-up is guaranteed, customers can be confident that their laboratory scale development efforts will scale to pilot and production volumes.
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