Pfaudler TCUs heat and cool AE 2500 reactors

A Swedish manufacturer of drug ingredients is using three Pfaudler closed-loop Thermal Control Units (TCUs) to control AE 2500 reactors (glass-lined and hastelloy) in hazardous areas.

Complete with expansion tanks and control systems, the flexibility of Pfaudler's modular-design TCU allows combinations of the primary heating and cooling services to be controlled by a single unit, utilising steam for heating and glycol for cooling.

This single-fluid system is suitable for heating and cooling all types of jacketed vessels, from glass-lined and alloy reactors to filter driers, evaporators and condenser loops.

It benefits from smooth and continuous temperature control, with no gaps, because there are no fluid changeovers.

With no thermal shock to vessels and no interruption to processes, Pfaudler's TCU eliminates off-batches because it removes hot-spots, resulting in enhanced quality and an enhanced product yield.

Because the yield is maximised without adding excess reactants, considerable savings can be made on raw materials.

It is suitable for cold operating temperatures required by today's new chemical formulas and reactions.

The repeatability and accurate recordable measurement of Pfaudler's TCU meets FDA requirements and benefits from accurate temperature control to +/-1C, without any risk to the reactor.

As standard, the TCU operates in the -29C to +200C temperature range, although the introduction of silicon-based thermal fluids has enabled Pfaudler to develop and provide units that allow heating to 400C and chilling to -100C.

The TCU can control specific exothermic and endothermic reactions, or be programmed to follow specific heating and cooling trends to match process requirements that will improve product quality and yield.

Compared with conventional jacket services, the TCU offers much improved batch-to-batch repeatability, often a requirement for FDA approval of processes.

Back to top