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News Release from: Thermo Fisher Scientific (Mass Spectrometry) | Subject: BioWorks 3.3
Edited by the Processingtalk Editorial
Team on 27 October 2006
Protein identification and quantitation
software
Thermo Electron, world leader in analytical instrumentation and software, has extended its protein identification and quantitation software package with the newly designed BioWorks 3.3
Thermo Electron Corporation, world leader in analytical instrumentation and software, has extended its protein identification and quantitation software package with the newly designed BioWorks 3.3 Featuring unique PepQuan capabilities, BioWorks 3.3 enables automated quantitative analysis of iTRAQ, SILAC and ICAT labeled samples, as well as label-free quantitation techniques
This article was originally published on Processingtalk on 17 Mar 2008 at 8.00am (UK)
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With new pre-search and post-search filters, BioWorks 3.3 removes unwanted spectra from the search resulting in faster search times, allowing users to focus only on the proteins of interest.
Reporting and documenting results is also improved with the new software package.
Spectra and tables can be quickly and easily transferred to Microsoft Office documents, while the new Protein Report feature enables printing of data directly from search results or the creation of PDF files.
BioWorks 3.3 features the Sequest protein search algorithm, which automatically identifies proteins by comparing experimental tandem mass spectrometry (MS/MS) data with standard protein and DNA databases.
It can analyse a single spectrum or an entire LC/MS/MS data set containing spectra from a mixture of proteins.
The proprietary "cross-correlation" identification algorithm within Sequest extracts information and correctly identifies proteins even at low concentrations.
Accurate mass capability is also incorporated in the new BioWorks 3.3 software package to enable Sequest searching on data acquired using the Thermo hybrid mass spectrometers.
The new software package can also process datasets acquired using vMALDI equipped LTQ XL systems.
Featuring enhanced Sequest Queue and Batch Search capabilities, users will also be able to launch searches on Mascot server from Bioworks 3.3 and compare Sequest and Mascot search results.
The new Bioworks 3.3 is the latest version of this software enabling protein identification and quantitation.
Providing tools for automated analysis of iTRAQ labeled samples, as well as SILAC and metabolic labeling experiments, this software package offers increased confidence in protein identification.
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